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The p16(INK4A) tumor suppressor regulates cellular oxidative stress

Mutations or deletions in the cyclin-dependent kinase inhibitor p16(INK4A) are associated with multiple cancer types, but more commonly found in melanoma tumors and associated with familial melanoma predisposition. Although p16 is thought to function as a tumor suppressor by negatively regulating th...

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Autors principals: Jenkins, Noah C., Liu, Tong, Cassidy, Pamela, Leachman, Sancy A., Boucher, Kenneth M., Goodson, Agnessa Gadeliya, Samadashwily, George, Grossman, Douglas
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003740/
https://ncbi.nlm.nih.gov/pubmed/20838381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2010.419
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