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Nanometer propagation of millisecond motions in V-type allostery

Imidazole glycerol phosphate synthase (IGPS) is a V-type allosteric enzyme, which is catalytically inactive for glutamine hydrolysis until the allosteric effector, N’-[(5′-phosphoribulosyl)formimino]-5-aminoimidazole-4-carboxamide-ribonucleotide (PRFAR) binds 30 Å away. In the apo state, NMR relaxat...

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Bibliografiske detaljer
Main Authors: Lipchock, James, Loria, J. Patrick
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003306/
https://ncbi.nlm.nih.gov/pubmed/21134639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2010.09.020
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