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Millisecond dynamics in the allosteric enzyme imidazole glycerol phosphate synthase (IGPS) from Thermotoga maritima

IGPS is a 51 kDa heterodimeric enzyme comprised of two proteins, HisH and HisF, that catalyze the hydrolysis of glutamine to produce NH(3) in the HisH active site and the cyclization of ammonia with N’-[(5’-phosphoribulosyl)formimino]-5-aminoimidazole-4-carboxamide-ribonucleotide (PRFAR) in HisF to...

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Bibliografiske detaljer
Main Authors: Lipchock, James, Loria, J. Patrick
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2918893/
https://ncbi.nlm.nih.gov/pubmed/19565337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10858-009-9337-8
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