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Millisecond dynamics in the allosteric enzyme imidazole glycerol phosphate synthase (IGPS) from Thermotoga maritima

IGPS is a 51 kDa heterodimeric enzyme comprised of two proteins, HisH and HisF, that catalyze the hydrolysis of glutamine to produce NH(3) in the HisH active site and the cyclization of ammonia with N’-[(5’-phosphoribulosyl)formimino]-5-aminoimidazole-4-carboxamide-ribonucleotide (PRFAR) in HisF to...

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Détails bibliographiques
Auteurs principaux: Lipchock, James, Loria, J. Patrick
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2918893/
https://ncbi.nlm.nih.gov/pubmed/19565337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10858-009-9337-8
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