Allosteric pathways in imidazole glycerol phosphate synthase

Protein allosteric pathways are investigated in the imidazole glycerol phosphate synthase heterodimer in an effort to elucidate how the effector (PRFAR, N′-[(5′-phosphoribulosyl)formimino]-5-aminoimidazole-4-carboxamide ribonucleotide) activates glutaminase catalysis at a distance of 25 Å from the g...

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Autores principales: Rivalta, Ivan, Sultan, Mohammad M., Lee, Ning-Shiuan, Manley, Gregory A., Loria, J. Patrick, Batista, Victor S.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2012
Materias:
PNAS Plus
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365145/
https://ncbi.nlm.nih.gov/pubmed/22586084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1120536109
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