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Histone H3K27ac separates active from poised enhancers and predicts developmental state

Developmental programs are controlled by transcription factors and chromatin regulators, which maintain specific gene expression programs through epigenetic modification of the genome. These regulatory events at enhancers contribute to the specific gene expression programs that determine cell state...

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Autores principales: Creyghton, Menno P., Cheng, Albert W., Welstead, G. Grant, Kooistra, Tristan, Carey, Bryce W., Steine, Eveline J., Hanna, Jacob, Lodato, Michael A., Frampton, Garrett M., Sharp, Phillip A., Boyer, Laurie A., Young, Richard A., Jaenisch, Rudolf
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003124/
https://ncbi.nlm.nih.gov/pubmed/21106759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1016071107
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