Histone H3K27ac separates active from poised enhancers and predicts developmental state

Developmental programs are controlled by transcription factors and chromatin regulators, which maintain specific gene expression programs through epigenetic modification of the genome. These regulatory events at enhancers contribute to the specific gene expression programs that determine cell state...

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Main Authors: Creyghton, Menno P., Cheng, Albert W., Welstead, G. Grant, Kooistra, Tristan, Carey, Bryce W., Steine, Eveline J., Hanna, Jacob, Lodato, Michael A., Frampton, Garrett M., Sharp, Phillip A., Boyer, Laurie A., Young, Richard A., Jaenisch, Rudolf
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2010
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003124/
https://ncbi.nlm.nih.gov/pubmed/21106759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1016071107
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