Histone H3K27ac separates active from poised enhancers and predicts developmental state

Developmental programs are controlled by transcription factors and chromatin regulators, which maintain specific gene expression programs through epigenetic modification of the genome. These regulatory events at enhancers contribute to the specific gene expression programs that determine cell state...

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Autors principals: Creyghton, Menno P., Cheng, Albert W., Welstead, G. Grant, Kooistra, Tristan, Carey, Bryce W., Steine, Eveline J., Hanna, Jacob, Lodato, Michael A., Frampton, Garrett M., Sharp, Phillip A., Boyer, Laurie A., Young, Richard A., Jaenisch, Rudolf
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2010
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003124/
https://ncbi.nlm.nih.gov/pubmed/21106759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1016071107
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