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X-linked H3K27me3 demethylase Utx is required for embryonic development in a sex-specific manner

Embryogenesis requires the timely and coordinated activation of developmental regulators. It has been suggested that the recently discovered class of histone demethylases (UTX and JMJD3) that specifically target the repressive H3K27me3 modification play an important role in the activation of “bivale...

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Autors principals: Welstead, G. Grant, Creyghton, Menno P., Bilodeau, Steve, Cheng, Albert W., Markoulaki, Styliani, Young, Richard A., Jaenisch, Rudolf
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3420177/
https://ncbi.nlm.nih.gov/pubmed/22826230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1210787109
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