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X-linked H3K27me3 demethylase Utx is required for embryonic development in a sex-specific manner

Embryogenesis requires the timely and coordinated activation of developmental regulators. It has been suggested that the recently discovered class of histone demethylases (UTX and JMJD3) that specifically target the repressive H3K27me3 modification play an important role in the activation of “bivale...

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Bibliografiske detaljer
Main Authors: Welstead, G. Grant, Creyghton, Menno P., Bilodeau, Steve, Cheng, Albert W., Markoulaki, Styliani, Young, Richard A., Jaenisch, Rudolf
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3420177/
https://ncbi.nlm.nih.gov/pubmed/22826230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1210787109
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