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X-linked H3K27me3 demethylase Utx is required for embryonic development in a sex-specific manner

Embryogenesis requires the timely and coordinated activation of developmental regulators. It has been suggested that the recently discovered class of histone demethylases (UTX and JMJD3) that specifically target the repressive H3K27me3 modification play an important role in the activation of “bivale...

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Main Authors: Welstead, G. Grant, Creyghton, Menno P., Bilodeau, Steve, Cheng, Albert W., Markoulaki, Styliani, Young, Richard A., Jaenisch, Rudolf
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3420177/
https://ncbi.nlm.nih.gov/pubmed/22826230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1210787109
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