Mechanism of action and inhibition of dehydrosqualene synthase

“Head-to-head” terpene synthases catalyze the first committed steps in sterol and carotenoid biosynthesis: the condensation of two isoprenoid diphosphates to form cyclopropylcarbinyl diphosphates, followed by ring opening. Here, we report the structures of Staphylococcus aureus dehydrosqualene synth...

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Detaylı Bibliyografya
Asıl Yazarlar: Lin, Fu-Yang, Liu, Chia-I, Liu, Yi-Liang, Zhang, Yonghui, Wang, Ke, Jeng, Wen-Yih, Ko, Tzu-Ping, Cao, Rong, Wang, Andrew H.-J., Oldfield, Eric
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2010
Konular:
Physical Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003041/
https://ncbi.nlm.nih.gov/pubmed/21098670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1010907107
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