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A hereditary spastic paraplegia mutation in kinesin-1A/KIF5A disrupts neurofilament transport

BACKGROUND: Hereditary spastic paraplegias are a group of neurological disorders characterized by progressive distal degeneration of the longest ascending and descending axons in the spinal cord, leading to lower limb spasticity and weakness. One of the dominantly inherited forms of this disease (sp...

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Sonraí Bibleagrafaíochta
Main Authors: Wang, Lina, Brown, Anthony
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2010
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000839/
https://ncbi.nlm.nih.gov/pubmed/21087519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-5-52
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