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Structural consequences of hereditary spastic paraplegia disease-related mutations in kinesin
A wide range of mutations in the kinesin motor Kif5A have been linked to a neuronal disorder called hereditary spastic paraplegia (HSP). The position of these mutations can vary, and a range of different motile behaviors have been observed, indicating that the HSP mutants can alter distinct aspects...
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| I publikationen: | Proc Natl Acad Sci U S A |
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| Huvudupphovsmän: | , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
National Academy of Sciences
2018
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6243270/ https://ncbi.nlm.nih.gov/pubmed/30366951 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1810622115 |
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