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Mechanistic basis of propofol-induced disruption of kinesin processivity

Propofol is a widely used general anesthetic to induce and maintain anesthesia, and its effects are thought to occur through impact on the ligand-gated channels including the GABA(A) receptor. Propofol also interacts with a large number of proteins including molecular motors and inhibits kinesin pro...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Dutta, Mandira, Gilbert, Susan P., Onuchic, José N., Jana, Biman
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7865149/
https://ncbi.nlm.nih.gov/pubmed/33495322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2023659118
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