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Common general anesthetic propofol impairs kinesin processivity

Propofol is the most widely used i.v. general anesthetic to induce and maintain anesthesia. It is now recognized that this small molecule influences ligand-gated channels, including the GABA(A) receptor and others. Specific propofol binding sites have been mapped using photoaffinity ligands and muta...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Bensel, Brandon M., Guzik-Lendrum, Stephanie, Masucci, Erin M., Woll, Kellie A., Eckenhoff, Roderic G., Gilbert, Susan P.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2017
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5448234/
https://ncbi.nlm.nih.gov/pubmed/28484025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1701482114
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