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Common general anesthetic propofol impairs kinesin processivity

Propofol is the most widely used i.v. general anesthetic to induce and maintain anesthesia. It is now recognized that this small molecule influences ligand-gated channels, including the GABA(A) receptor and others. Specific propofol binding sites have been mapped using photoaffinity ligands and muta...

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Podrobná bibliografie
Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Bensel, Brandon M., Guzik-Lendrum, Stephanie, Masucci, Erin M., Woll, Kellie A., Eckenhoff, Roderic G., Gilbert, Susan P.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5448234/
https://ncbi.nlm.nih.gov/pubmed/28484025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1701482114
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