Characterization of kinesin switch I mutations that cause hereditary spastic paraplegia

Kif5A is a neuronally-enriched isoform of the Kinesin-1 family of cellular transport motors. 23 separate mutations in the motor domain of Kif5A have been identified in patients with the complicated form of hereditary spastic paraplegia (HSP). We performed in vitro assays on dimeric recombinant Kif5A...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Jennings, Scott, Chenevert, Madeline, Liu, Liqiong, Mottamal, Madhusoodanan, Wojcik, Edward J., Huckaba, Thomas M.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5498027/
https://ncbi.nlm.nih.gov/pubmed/28678816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0180353
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker