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A hereditary spastic paraplegia mutation in kinesin-1A/KIF5A disrupts neurofilament transport
BACKGROUND: Hereditary spastic paraplegias are a group of neurological disorders characterized by progressive distal degeneration of the longest ascending and descending axons in the spinal cord, leading to lower limb spasticity and weakness. One of the dominantly inherited forms of this disease (sp...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3000839/ https://ncbi.nlm.nih.gov/pubmed/21087519 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-5-52 |
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