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A hereditary spastic paraplegia mutation in kinesin-1A/KIF5A disrupts neurofilament transport

BACKGROUND: Hereditary spastic paraplegias are a group of neurological disorders characterized by progressive distal degeneration of the longest ascending and descending axons in the spinal cord, leading to lower limb spasticity and weakness. One of the dominantly inherited forms of this disease (sp...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Wang, Lina, Brown, Anthony
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000839/
https://ncbi.nlm.nih.gov/pubmed/21087519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-5-52
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