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A Chemical Library Approach to Organic-Modified Peptide Ligands for PDZ Domain Proteins: A Synthetic, Thermodynamic and Structural Investigation

PDZ domains are members of the protein interaction domain family,[1] semi-autonomous modules embedded within larger signaling proteins that impart a degree of exclusivity to the binding properties of their hosts. As mediators of mammalian protein-protein interactions that number in the hundreds, PDZ...

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מידע ביבליוגרפי
Main Authors: Udugamasooriya, D. Gomika, Sharma, Sudhir C., Spaller, Mark R.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2008
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000795/
https://ncbi.nlm.nih.gov/pubmed/18506876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.200800126
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