Inflammasome Sensor Nlrp1b-Dependent Resistance to Anthrax Is Mediated by Caspase-1, IL-1 Signaling and Neutrophil Recruitment

Bacillus anthracis infects hosts as a spore, germinates, and disseminates in its vegetative form. Production of anthrax lethal and edema toxins following bacterial outgrowth results in host death. Macrophages of inbred mouse strains are either sensitive or resistant to lethal toxin depending on whet...

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Detaylı Bibliyografya
Asıl Yazarlar: Moayeri, Mahtab, Crown, Devorah, Newman, Zachary L., Okugawa, Shu, Eckhaus, Michael, Cataisson, Christophe, Liu, Shihui, Sastalla, Inka, Leppla, Stephen H.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2010
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000361/
https://ncbi.nlm.nih.gov/pubmed/21170303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1001222
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