Anthrax Edema Toxin Impairs Clearance in Mice

The anthrax edema toxin (ET) of Bacillus anthracis is composed of the receptor-binding component protective antigen (PA) and of the adenylyl cyclase catalytic moiety, edema factor (EF). Uptake of ET into cells raises intracellular concentrations of the secondary messenger cyclic AMP, thereby impairi...

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Detalhes bibliográficos
Main Authors: Sastalla, Inka, Tang, Shixing, Crown, Devorah, Liu, Shihui, Eckhaus, Michael A., Hewlett, Indira K., Leppla, Stephen H., Moayeri, Mahtab
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Molecular Pathogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264307/
https://ncbi.nlm.nih.gov/pubmed/22104108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.05947-11
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