Anthrax Edema Toxin Impairs Clearance in Mice

The anthrax edema toxin (ET) of Bacillus anthracis is composed of the receptor-binding component protective antigen (PA) and of the adenylyl cyclase catalytic moiety, edema factor (EF). Uptake of ET into cells raises intracellular concentrations of the secondary messenger cyclic AMP, thereby impairi...

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Bibliographic Details
Main Authors: Sastalla, Inka, Tang, Shixing, Crown, Devorah, Liu, Shihui, Eckhaus, Michael A., Hewlett, Indira K., Leppla, Stephen H., Moayeri, Mahtab
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2012
Subjects:
Molecular Pathogenesis
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264307/
https://ncbi.nlm.nih.gov/pubmed/22104108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.05947-11
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