Anthrax Edema Toxin Impairs Clearance in Mice

The anthrax edema toxin (ET) of Bacillus anthracis is composed of the receptor-binding component protective antigen (PA) and of the adenylyl cyclase catalytic moiety, edema factor (EF). Uptake of ET into cells raises intracellular concentrations of the secondary messenger cyclic AMP, thereby impairi...

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Bibliografiske detaljer
Main Authors: Sastalla, Inka, Tang, Shixing, Crown, Devorah, Liu, Shihui, Eckhaus, Michael A., Hewlett, Indira K., Leppla, Stephen H., Moayeri, Mahtab
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2012
Fag:
Molecular Pathogenesis
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264307/
https://ncbi.nlm.nih.gov/pubmed/22104108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.05947-11
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