Anthrax toxin targeting of myeloid cells through the CMG2 receptor is essential for establishment of Bacillus anthracis infections in mice

Bacillus anthracis kills through a combination of bacterial infection and toxemia. Anthrax toxin working via the CMG2 receptor mediates lethality late in infection, but its roles early in infection remain unclear. We generated myeloid-lineage specific CMG2-deficient mice to examine the roles of macr...

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Bibliografske podrobnosti
Main Authors: Liu, Shihui, Miller-Randolph, Sharmina, Crown, Devorah, Moayeri, Mahtab, Sastalla, Inka, Okugawa, Shu, Leppla, Stephen H.
Format: Artigo
Jezik:Inglês
Izdano: 2010
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032408/
https://ncbi.nlm.nih.gov/pubmed/21075356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2010.10.004
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