Capillary morphogenesis protein-2 is the major receptor mediating lethality of anthrax toxin in vivo

Anthrax toxin, a major virulence factor of Bacillus anthracis, gains entry into target cells by binding to either of 2 von Willebrand factor A domain-containing proteins, tumor endothelium marker-8 (TEM8) and capillary morphogenesis protein-2 (CMG2). The wide tissue expression of TEM8 and CMG2 sugge...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Liu, Shihui, Crown, Devorah, Miller-Randolph, Sharmina, Moayeri, Mahtab, Wang, Hailun, Hu, Haijing, Morley, Thomas, Leppla, Stephen H.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2009
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2718377/
https://ncbi.nlm.nih.gov/pubmed/19617532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0905409106
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