Anthrax Edema Toxin Impairs Clearance in Mice

The anthrax edema toxin (ET) of Bacillus anthracis is composed of the receptor-binding component protective antigen (PA) and of the adenylyl cyclase catalytic moiety, edema factor (EF). Uptake of ET into cells raises intracellular concentrations of the secondary messenger cyclic AMP, thereby impairi...

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Autors principals: Sastalla, Inka, Tang, Shixing, Crown, Devorah, Liu, Shihui, Eckhaus, Michael A., Hewlett, Indira K., Leppla, Stephen H., Moayeri, Mahtab
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2012
Matèries:
Molecular Pathogenesis
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264307/
https://ncbi.nlm.nih.gov/pubmed/22104108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.05947-11
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