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Anthrax Lethal Factor Cleavage of Nlrp1 Is Required for Activation of the Inflammasome
NOD-like receptor (NLR) proteins (Nlrps) are cytosolic sensors responsible for detection of pathogen and danger-associated molecular patterns through unknown mechanisms. Their activation in response to a wide range of intracellular danger signals leads to formation of the inflammasome, caspase-1 act...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3315489/ https://ncbi.nlm.nih.gov/pubmed/22479187 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002638 |
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