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Deletion of CDKAL1 Affects Mitochondrial ATP Generation and First-Phase Insulin Exocytosis
BACKGROUND: A variant of the CDKAL1 gene was reported to be associated with type 2 diabetes and reduced insulin release in humans; however, the role of CDKAL1 in β cells is largely unknown. Therefore, to determine the role of CDKAL1 in insulin release from β cells, we studied insulin release profile...
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| Main Authors: | , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3000340/ https://ncbi.nlm.nih.gov/pubmed/21151568 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015553 |
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