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Pregnane X Receptor as a Therapeutic Target to Inhibit Androgen Activity
The androgen-androgen receptor signaling pathway plays an important role in the pathogenesis of prostate cancer. Accordingly, androgen deprivation has been the most effective endocrine therapy for hormone-dependent prostate cancer. Here, we report a novel pregnane X receptor (PXR)-mediated and metab...
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| Autors principals: | , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Endocrine Society
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2999492/ https://ncbi.nlm.nih.gov/pubmed/20962047 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2010-0708 |
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