SUMO Losing Balance: SUMO Proteases Disrupt SUMO Homeostasis to Facilitate Cancer Development and Progression

Small ubiquitin-like modifiers (SUMO) conjugation to cellular proteins is a reversible posttranslational modification that mediates the protein’s function, subcellular localization, and/or expression. The SUMO proteases (SENP) deconjugate modified proteins and thus are critical for maintaining the l...

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Bibliografiske detaljer
Main Authors: Bawa-Khalfe, Tasneem, Yeh, Edward T.H.
Format: Artigo
Sprog:Inglês
Udgivet: SAGE Publications 2010
Fag:
Monographs
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998238/
https://ncbi.nlm.nih.gov/pubmed/21152235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601910382555
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