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Balancing Act during Development: Lessons from a SUMO-less SF-1
When a transcription factor is modified by SUMO (small ubiquitin-like modifier), this usually represses its transcriptional activity. In this issue of Developmental Cell, Lee et al. (2011) use a knock-in mouse model to show that SUMO-less SF-1 binds and activates inappropriate targets, causing chang...
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| Main Authors: | , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2011
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3162251/ https://ncbi.nlm.nih.gov/pubmed/21839916 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2011.07.015 |
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