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SUMO-specific Protease 1 is Essential for Stabilization of Hypoxia-inducible factor-1α During Hypoxia
SUMOylation is a dynamic process, catalyzed by SUMO-specific E1, E2, and E3s and reversed by Sentrin/SUMO-specific proteases (SENPs). However, the physiologic consequence of SUMOylation and de-SUMOylation is not fully understood. Embryos with inactivated mouse SENP1 locus showed severe fetal anemia...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2007
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2128732/ https://ncbi.nlm.nih.gov/pubmed/17981124 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2007.08.045 |
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