SUMO-specific Protease 1 Regulates Mitochondrial Biogenesis through PGC-1α

Peroxisome proliferator-activated receptor γ (PPARγ) coactivator 1α (PGC-1α) is a master regulator of mitochondrial biogenesis in response to changes in the cellular environment, physiological or pathological status of mammals. PGC-1α is known to be modified by SUMO (Small Ubiquitin-like Modifier)....

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Detalhes bibliográficos
Main Authors: Cai, Rong, Yu, Tingting, Huang, Chao, Xia, Xuefeng, Liu, Xiaobing, Gu, Jianmin, Xue, Song, Yeh, Edward T.H., Cheng, Jinke
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3531759/
https://ncbi.nlm.nih.gov/pubmed/23152500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.422626
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