SUMO-Specific Protease 1 Is Critical for Early Lymphoid Development through Regulation of STAT5 Activation

Small ubiquitin-like modifier (SUMO) modification has emerged as an important regulatory mechanism during embryonic development. However, it is not known whether SUMOylation plays a role in the development of the immune system. Here, we show that SUMO-specific protease 1 (SENP1) is essential for the...

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Main Authors: Van Nguyen, Thang, Angkasekwinai, Pornpimon, Dou, Hong, Lin, Feng-Ming, Lu, Long-Sheng, Cheng, Jinke, Chin, Y. Eugene, Dong, Chen, Yeh, Edward T.H.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3269036/
https://ncbi.nlm.nih.gov/pubmed/22284677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.12.026
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