Novel SUMO-Protease SENP7S Regulates β-catenin Signaling and Mammary Epithelial Cell Transformation

SUMO post-translational modification of proteins or SUMOylation ensures normal cell function. Disruption of SUMO dynamics prompts various pathophysiological conditions, including cancer. The burden of deSUMOylating the large SUMO-proteome rests on 6 full-length mammalian SUMO-proteases or SENP. Whil...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Karami, Samaneh, Lin, Feng-Ming, Kumar, Santosh, Bahnassy, Shaymaa, Thangavel, Hariprasad, Quttina, Maram, Li, Yue, Ren, Jing, Bawa-Khalfe, Tasneem
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5399363/
https://ncbi.nlm.nih.gov/pubmed/28429743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep46477
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