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SUMOylation of HP1α supports association with ncRNA to define responsiveness of breast cancer cells to chemotherapy

Epigenetic reprogramming allows cancer cells to bypass normal checkpoints and potentiate aberrant proliferation. Several chromatin regulators are subject to reversible SUMO-modification but little is known about how SUMOylation of chromatin-remodelers modulates the cancer epigenome. Recently, we dem...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Lin, Feng-Ming, Kumar, Santosh, Ren, Jing, Karami, Samaneh, Bahnassy, Shaymaa, Li, Yue, Zheng, Xiaofeng, Wang, Jing, Bawa-Khalfe, Tasneem
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5058684/
https://ncbi.nlm.nih.gov/pubmed/27107417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8733
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