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DNA bending and unbending by MutS govern mismatch recognition and specificity
DNA mismatch repair is central to the maintenance of genomic stability. It is initiated by the recognition of base–base mismatches and insertion/deletion loops by the family of MutS proteins. Subsequently, ATP induces a unique conformational change in the MutS–mismatch complex but not in the MutS–ho...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2003
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC299810/ https://ncbi.nlm.nih.gov/pubmed/14634210 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2433654100 |
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