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Functions of disordered regions in mammalian early base excision repair proteins

Reactive oxygen species, generated endogenously and induced as a toxic response, produce several dozen oxidized or modified bases and/or single-strand breaks in mammalian and other genomes. These lesions are predominantly repaired via the conserved base excision repair (BER) pathway. BER is initiate...

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Hlavní autoři: Hegde, Muralidhar L., Hazra, Tapas K., Mitra, Sankar
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996047/
https://ncbi.nlm.nih.gov/pubmed/20714778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-010-0485-5
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