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Structure of rotavirus outer-layer protein VP7 bound with a neutralizing Fab
The crystal structure of rotavirus VP7 bound with the Fab from a neutralizing monoclonal shows the mechanism by which members of a large class of neutralizing antibodies inhibit rotavirus infection, indicates how withdrawal of Ca(2+) ions becomes an uncoating trigger during cell entry, and provides...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2995306/ https://ncbi.nlm.nih.gov/pubmed/19520960 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1170481 |
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