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Structure of rotavirus outer-layer protein VP7 bound with a neutralizing Fab

The crystal structure of rotavirus VP7 bound with the Fab from a neutralizing monoclonal shows the mechanism by which members of a large class of neutralizing antibodies inhibit rotavirus infection, indicates how withdrawal of Ca(2+) ions becomes an uncoating trigger during cell entry, and provides...

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Bibliografische gegevens
Hoofdauteurs: Aoki, Scott T., Settembre, Ethan, Trask, Shane D., Greenberg, Harry B., Harrison, Stephen C., Dormitzer, Philip R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2009
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995306/
https://ncbi.nlm.nih.gov/pubmed/19520960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1170481
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