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Proteolysis of Monomeric Recombinant Rotavirus VP4 Yields an Oligomeric VP5* Core
Rotavirus particles are activated for cell entry by trypsin cleavage of the outer capsid spike protein, VP4, into a hemagglutinin, VP8*, and a membrane penetration protein, VP5*. We have purified rhesus rotavirus VP4, expressed in baculovirus-infected insect cells. Purified VP4 is a soluble, elongat...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC114969/ https://ncbi.nlm.nih.gov/pubmed/11462006 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.16.7339-7350.2001 |
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