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Effect of Mutations in VP5* Hydrophobic Loops on Rotavirus Cell Entry

Experiments in cell-free systems have demonstrated that the VP5* cleavage fragment of the rotavirus spike protein, VP4, undergoes a foldback rearrangement that translocates three clustered hydrophobic loops from one end of the molecule to the other. This conformational change resembles the foldback...

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Bibliografiske detaljer
Main Authors: Kim, Irene S., Trask, Shane D., Babyonyshev, Marina, Dormitzer, Philip R., Harrison, Stephen C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876642/
https://ncbi.nlm.nih.gov/pubmed/20375171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02461-09
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