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Structural Basis of Ubiquitin Recognition by Translesion Synthesis DNA Polymerase ι
Cells have evolved mutagenic bypass mechanisms that prevent stalling of the replication machinery at DNA lesions. This process, translesion DNA synthesis (TLS), involves switching from high-fidelity DNA polymerases to specialized DNA polymerases that replicate through a variety of DNA lesions. In eu...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2995291/ https://ncbi.nlm.nih.gov/pubmed/21049971 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi101303t |
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