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Beta-Cell Selective K(ATP)-Channel Activation Protects Beta-Cells and Human Islets from Human Islet Amyloid Polypeptide Induced Toxicity
BACKGROUND AND AIMS: In type 2 diabetes mellitus (T2DM) chronic beta-cell stimulation and oligomers of aggregating human islet amyloid polypeptide (h-IAPP) cause beta-cell dysfunction and induce beta-cell apoptosis. Therefore we asked whether beta-cell rest prevents h-IAPP induced beta-cell apoptosi...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2995001/ https://ncbi.nlm.nih.gov/pubmed/20619299 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.regpep.2010.06.009 |
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