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Idealized models of protofilaments of human islet amyloid polypeptide
Fibrils formed by assembly of human islet amyloid polypeptide (hIAPP) are found in most patients with type II diabetes. Structurally, these fibrils are composed of multiple protofilaments and are characterized by extended beta sheets, variable helical twists, and different morphologies. We have prev...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3522432/ https://ncbi.nlm.nih.gov/pubmed/23116372 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ci300300e |
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