ロード中...

Exendin-4 increases islet amyloid deposition but offsets the resultant beta-cell toxicity in human islet amyloid polypeptide transgenic mouse islets

AIMS/HYPOTHESIS: In type 2 diabetes, aggregation of islet amyloid polypeptide (IAPP) into amyloid is associated with beta-cell loss. As IAPP is co-secreted with insulin, we hypothesised that IAPP secretion is necessary for amyloid formation, and treatments which increase insulin (and IAPP) secretion...

詳細記述

保存先:
書誌詳細
主要な著者: Aston-Mourney, K., Hull, R. L., Zraika, S., Udayasankar, J., Subramanian, S. L., Kahn, S. E.
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3220951/
https://ncbi.nlm.nih.gov/pubmed/21484213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-011-2143-3
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!