ロード中...
Exendin-4 increases islet amyloid deposition but offsets the resultant beta-cell toxicity in human islet amyloid polypeptide transgenic mouse islets
AIMS/HYPOTHESIS: In type 2 diabetes, aggregation of islet amyloid polypeptide (IAPP) into amyloid is associated with beta-cell loss. As IAPP is co-secreted with insulin, we hypothesised that IAPP secretion is necessary for amyloid formation, and treatments which increase insulin (and IAPP) secretion...
保存先:
| 主要な著者: | , , , , , |
|---|---|
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2011
|
| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3220951/ https://ncbi.nlm.nih.gov/pubmed/21484213 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-011-2143-3 |
| タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|