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Expression and distribution of the class III ubiquitin-conjugating enzymes in the retina

PURPOSE: Mounting evidence implicates chronic oxidative stress as a significant pathogenic factor in the development and progression of retinopathies, including age-related macular degeneration (AMD). The age-dependent toxic accumulation of oxidatively damaged proteins, lipids, and DNA in susceptibl...

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Detalhes bibliográficos
Main Authors: Mirza, Saima, Plafker, Kendra S., Aston, Christopher, Plafker, Scott M.
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Vision 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2994761/
https://ncbi.nlm.nih.gov/pubmed/21139979
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