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Loss of the ubiquitin conjugating enzyme UBE2E3 induces cellular senescence

Cellular senescence plays essential roles in tissue homeostasis as well as a host of diseases ranging from cancers to age-related neurodegeneration. Various molecular pathways can induce senescence and these different pathways dictate the phenotypic and metabolic changes that accompany the transitio...

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Udgivet i:Redox Biol
Main Authors: Plafker, Kendra S., Zyla, Katarzyna, Berry, William, Plafker, Scott M.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6007080/
https://ncbi.nlm.nih.gov/pubmed/29879550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2018.05.008
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