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The ubiquitin-conjugating enzyme UBE2E3 and its import receptor importin-11 regulate the localization and activity of the antioxidant transcription factor NRF2

The transcription factor NF-E2 p45–related factor (Nrf2) induces the expression of cytoprotective proteins that maintain and restore redox homeostasis. Nrf2 levels and activity are tightly regulated, and three subcellular populations of the transcription factor have been identified. During homeostas...

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Bibliografski detalji
Izdano u:Mol Biol Cell
Glavni autori: Plafker, Kendra S., Plafker, Scott M.
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Cell Biology 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294679/
https://ncbi.nlm.nih.gov/pubmed/25378586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-06-1057
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