Cutting Edge: Cytosolic Bacterial DNA Activates the Inflammasome via Aim2

Pathogens are detected by pattern recognition receptors that, upon activation, orchestrate an appropriate immune response. The TLRs and the nucleotide-binding oligomerization domain-like receptors (NLRs) are prototypic pattern recognition receptors that detect extracellular and cytosolic pathogens,...

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Autores principales: Warren, Sarah E., Armstrong, Abraham, Hamilton, M. Kristina, Mao, Dat P., Leaf, Irina A., Miao, Edward A., Aderem, Alan
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993756/
https://ncbi.nlm.nih.gov/pubmed/20562263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1000724
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