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Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome
The mammalian innate immune system uses Toll-like receptors (TLRs) and Nod-LRRs (NLRs) to detect microbial components during infection. Often these molecules work in concert; for example, the TLRs can stimulate the production of the proforms of the cytokines IL-1β and IL-18, whereas certain NLRs tri...
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| Päätekijät: | , , , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
National Academy of Sciences
2010
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2840275/ https://ncbi.nlm.nih.gov/pubmed/20133635 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0913087107 |
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