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Generation of a Listeria vaccine strain by enhanced Caspase-1 activation
The immunostimulatory properties conferred by vaccine adjuvants require Caspase-1 for processing of IL-1β and IL-18. Caspase-1 is activated in response to a breach of the cytosolic compartment by microbes and the process is initiated by intracellular pattern recognition receptors within inflammasome...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3375905/ https://ncbi.nlm.nih.gov/pubmed/21538346 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201041214 |
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