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Generation of a Listeria vaccine strain by enhanced Caspase-1 activation

The immunostimulatory properties conferred by vaccine adjuvants require Caspase-1 for processing of IL-1β and IL-18. Caspase-1 is activated in response to a breach of the cytosolic compartment by microbes and the process is initiated by intracellular pattern recognition receptors within inflammasome...

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Bibliografische gegevens
Hoofdauteurs: Warren, Sarah E., Duong, Hien, Mao, Dat Phat, Armstrong, Abraham, Rajan, Jayant, Miao, Edward A., Aderem, Alan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3375905/
https://ncbi.nlm.nih.gov/pubmed/21538346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201041214
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